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25 Jan 2019 20:01
In the early 1990s, major professional societies--including the American College of Obstetricians and Gynecologists, the American College of Physicians, and the American Heart Association--recommended hormone replacement therapy for all postmenopausal women, based on studies that showed it prevented both osteoporosis and heart disease. A decade later, as widespread use failed to produce the predicted cardiac benefits and unanticipated harms occurred, the recommendation was withdrawn.
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